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GI Module 9
Perfusion-first ? NGN-aligned

Inflammatory Bowel Disease

Crohn disease ? Ulcerative colitis
Progress
Crohn vs Ulcerative Colitis diagram
Transmural skip lesions in Crohn; continuous mucosal disease in UC.

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Safety first

Perfusion and absorption

??AGENT ENTEROCYTE ABSORBER

"I line the villi. I need perfusion to pull nutrients, water, and electrolytes. In UC, my mucosa gets ulcerated; in Crohn, transmural inflammation can fistula and steal my surface."

???AGENT IMMUNE SENTINEL

"I defend the gut. In IBD I overreact; perfusion loss worsens tissue injury. Steroids calm me but raise infection risk."

#Perfusion inputFactory partTissue OKTissue LOW/InflamedObservable cueNursing action + reason
1MAP and oxygenEnterocyte ATPGood absorptionPoor absorption, diarrheaLoose stool, weight lossHydrate, replace electrolytes; monitor MAP.
2NutrientsVillus surfaceIntact liningUlcerated mucosaBloody diarrhea (UC)Monitor blood loss; prepare for iron/PRBC per order.
3Venous returnWall drainageNormalTransmural edemaRLQ pain, fistula drainage (Crohn)Measure output; protect skin; nutrition support.
4Perfusion reserveColon smooth muscleNormal toneRisk of toxic megacolonFever, tachycardia, distention, painRapid notify, NPO, decompress per order, prepare OR?prevent perforation.

Complication bridge: Hypoperfusion with active inflammation leads to deep wall edema. In UC that can progress to toxic megacolon or perforation. In Crohn it can progress to fistula or abscess. Early MAP support together with inflammation control lowers these risks.

Layer view

Crohn: transmural, skip, fistula risk. UC: mucosal, continuous from rectum upward.

Crohn vs UC layer illustration

Quick Cue Radar

Fast map: cue to meaning to move.

Bloody diarrhea with urgency

Meaning: mucosal ulceration (likely UC).

Actions:
1) Monitor H/H and electrolytes
2) Administer steroids/5-ASA per order
3) Watch for toxic megacolon cues

Why:
1) Blood and fluid loss affect perfusion
2) Calms inflammation
3) Early catch prevents perforation.

RLQ pain, weight loss, fistula drainage

Meaning: Crohn transmural disease.

Actions:
1) Nutrition support (high-calorie, may need TPN if ordered)
2) Skin protection around fistula
3) Steroids/biologics per order

Why:
1) Malabsorption risk
2) Prevents skin breakdown
3) Calms immune overdrive.

Fever, tachycardia, distended tender abdomen

Meaning: possible toxic megacolon.

Actions:
1) Notify provider rapidly
2) Keep NPO
3) Prepare for imaging and possible surgery

Why:
1) High risk for perforation
2) Reduce risk aspiration/pressure
3) Rapid diagnosis needed.

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